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Highly sensitive detection for cocaine using an aptamer-modified molybdenum disulfide/gold nanoparticle microarray

Li Gao,Zebin Deng,Yuanwei Lin,Husseini Sulemana,Haixia Shi,Chaosheng Yu,Shuaijun Chen

NEW JOURNAL OF CHEMISTRY（2020）

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Abstract
The detection of cocaine based on an aptamer-modified molybdenum disulfide@gold nanoparticle (MoS2@AuNP) nanosheet array immobilized on aminated slides was achieved. Cocaine was detected using fluorescence energy resonance transfer between MoS2@AuNPs and an aptamer modified with Cy5. The method had a detection limit of 0.19388 nM for cocaine.
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Key words
disulfide/gold nanoparticle microarray,molybdenum disulfide/gold,cocaine,sensitive detection,aptamer-modified
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