The Use of Raman Spectroscopy in Cancer Diagnostics

Both Raman spectroscopy and surface-enhanced Raman spectroscopy (SERS) are proving to be invaluable tools in the field of biomedical research and clinical diagnostics. The robust, compact, fit-for-purpose Raman spectrometer designs are appropriate for use in surgical procedures to help surgeons assess tumors and allow rapid decisions to be made. Raman systems are also being developed for molecular diagnostic testing to detect and measure human cancer biomarkers. Based on the SERS technique, this approach potentially could change the way bioassays are performed to improve both the sensitivity and reliability of testing. The two applications highlighted in this review, together with other examples of the use of Raman spectrometry in biomedical research areas such as the identification of bacterial infections, are clearly going to make the technique an important part of the medical toolbox, as we continually strive to improve diagnostic techniques and bring a better health care system to patients.