Margin negative resection and pathologic downstaging with multiagent chemotherapy with or without radiotherapy in patients with localized pancreas cancer: A national cancer database analysis

Joseph A. Miccio,Wesley J. Talcott,Timil Patel,Henry S. Park,Michael Cecchini,Ronald R. Salem,Sajid A. Khan,Stacey Stein,Jeremy S. Kortmansky,Jill Lacy,Amol Narang,Joseph Herman,Salma K. Jabbour,Christopher L. Hallemeier,Kimberly Johung,Krishan R. Jethwa

Clinical and Translational Radiation Oncology（2021）

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摘要

•Complete resection is a potentially curative treatment for pancreatic cancer.•This report studies neoadjuvant chemotherapy with or without radiation.•The addition of radiation was associated with improved complete resection rates.•The addition of radiation was associated with improved pathologic down staging.

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R0,PDAC,MAC,RT,UVA,MVA,LR,OS,IQR,NCDB,AJCC,LVI,pCR

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