Anti-inflammatory constituents in the root and rhizome of Polygonum cuspidatum by UPLC-PDA-QTOF/MS and lipopolysaccharide-activated RAW264.7 macrophages
Journal of Pharmaceutical and Biomedical Analysis(2021)
Abstract
•An UPLC-Q-TOF/MS method was used to characterize the constituents in HZE-60.•5 constituents were quantitatively analyzed and compared in activity fractions.•Resveratrol, E-1-G and E-8-G were vital anti-inflammatory constituents in Hu-Zhang.
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Key words
HZE,UPLC-Q-TOF/MS,TCM,BPI,LOD,LOQ,S/N,RSD,LPS,ELISA,MCP-1
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