Effect of isotretinoin on induced tooth movement in rats

Ariane Ximenes Graciano Parra,Aline Cristina Batista Rodrigues Johann,Ana Maria Trindade Grégio Hardy,Layza Rossatto Oppitz,Cristiano Miranda Araujo,Orlando Motohiro Tanaka,Odilon Guariza Filho,Elisa Souza Camargo

American Journal of Orthodontics and Dentofacial Orthopedics（2021）

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摘要

•We evaluated the effect of isotretinoin (7.5 mg/kg) on tooth movement in rats.•Isotretinoin did not affect tooth displacement and collagen neoformation.•Isotretinoin did not affect bone resorption and the presence of hyaline areas.•Isotretinoin did not affect bone microarchitecture.•Isotretinoin (7.5 mg/kg) decreased root resorption in rats subjected to tooth movement.

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关键词

isotretinoin,tooth movement

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