Endometrial cancer: A systematic review of HE4, REM and REM-B

Manon Degez,Hélène Caillon,Anne Chauviré-Drouard,Maxime Leroy,David Lair,Norbert Winer,Thibault Thubert,Vincent Dochez

Clinica Chimica Acta（2021）

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Abstract

•HE4 appears to be the best marker for the diagnosis of endometrial cancer.•Algorithms such as REM and REM-B seem to be interesting tools.•HE4 is strongly associated with prognostic factors such as FIGO stage.•HE4 seems to be promising as a marker for predicting recurrence.

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Key words

HE4,Human epididymis protein 4,Endometrial cancer,Endometrial carcinoma,REM

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