Identification of novel Taz isoforms and functional comparison in pluripotency maintenance of mouse embryonic stem cells

Gene（2021）

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摘要

•Novel isoforms of Taz were identified in mouse embryonic stem cells.•All isoforms can activate transcription.•All isoforms can induce apoptosis and differentiation in unstable conditions.•One of them can function as constitutively active form.

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关键词

AS,mRNA,ESC,Taz,LIF,snRNA,Oct4,Sox2,STAT3,BMP,id,Yap,TEAD,TAD,EMT,CDS,NCBI,PCR,RACE,cDNA,KD,DOX,RFP,HEK293,OE,PI,qRT-PCR,Sox1,Gata6,Flk1,PTC,NMD

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