Lncrna Lncogd-1006 Alleviates Ogd-Induced Ischemic Brain Injury Regulating Apoptosis Through Mir-184-5p/Caap1 Axis

OBJECTIVE: This study aimed to explore the effect of long non-coding RNA (LncRNA) LncOGD-1006 to ischemic stroke and the possible mechanism.MATERIALS AND METHODS: The primary brain microvascular endothelial cells (bEnd.3) of oxygen-glucose deprivation (OGD) was used as a mimic of ischemic stroke in vitro.RESULTS: The results showed that LncOGD-1006 was upregulated in bEnd.3 after OGD-induced.CONCLUSIONS: LncOGD-1006 might act as a ceRNA to inhibit apoptosis in bEnd.3 cells by targeting miR-184-6p/CAAP1 pathway.