Mortality at one year follow-up in patients with chronic kidney disease stage 4

INTRODUCTION: Chronic Kidney Disease (CKD) is associated with an increased morbidity and mortality There arc few published reports on outcomes in non dialysis CKD patients in Latin-America. Our objective was to retrospectively assess in a cohort certain outcomes of CKD stage 4 with respect to different morbidities, mortality rate and renal replacement therapy onset: in one year of follow-up. RESULTS: We identified 154 patients, median follow-up tulle: 12 months, females 48% Median age: 81 years (interquartile range 74-85). Comorbidities. stroke 9.7% (5.6-15.7); coronary heart disease 25 3% (18 7-33); diabetes 26.6% (19 8-34 3); lipid disorders 55.8% (47.6-63.8); hypertension 93 5% (88 4-96.8); congestive heart failure 31 8% (24 6-39.8), tobacco 30.5% (23.4-38.4); overweight/obesity 27 9% (21.0-35.7). Mortality rate. 10.6 (6 71-17 88) General annual hospitalization rate: 16.44 (11.02-24.52), in cardiovascular unit. 10 27 (9.16-17.04); in kidney failure unit. 2 05 (0.66-6 37) The rate of renal replacement therapy onset was. 2.73 (1.08-7 29) The only independent variables with statistical significance for death in a one-way analysis were chronic heart failure and atrial fibrillation, although these did not stand for multivariate analysis CONCLUSIONS: CKD stage 4 patients are very old and present different comorbidities In one year of follow-up, one out of 37 may inmate dialysis, one out of 9 may die within a year, while one out of 6 may require hospital admission mainly due to cardiovascular disease The present results are important because there are few publications on this topic in Latin-America, and could be used as baseline reference for future programs.