Risk Method Assessment Of Coronary Heart Disease In Carriers Of Polymorphic Cardiogenic

RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES(2016)

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摘要
Due to the high prevalence of cardiovascular disease (CVD), including coronary heart disease (CHD) additional risk factors based on molecular genetics are currently explored. It is believed that the structure of the body and processes occurring in it are defined by a set of DNA of genes. It should be noted that each individual set of human genes and the DNA structure is not the structure of the absolute list of factors predetermine imbalance in these growth processes, but their role is very high. It is known that during the occurrence of different mutations, gene structure may be changed by substituting some amino acids by others. Thus, a gene polymorphism, and carriers of the same gene with a different set of amino acids may have a different risk of developing coronary heart disease. It follows that the genetic analysis reveals the individual predisposition to the emergence of genetically determined risk factors. The article is devoted to the development of a new method of assessing the current state of the cardiovascular system, as well as the degree of risk of CHD based on modern virtual information technology acquisition and processing of various types of cardiac data, including the results of the analysis of cardiogenic affecting the development of risk factors. Technical solution proposed by a team allows for remote monitoring of the patient's CVS through telemedicine technologies with portable Cardiosensor for transmission, processing and storage of information in databases (DB) "ARM-Cardiologist" to develop managed care decision based on the generated program CHD diagnosis based on proposed set of diagnostic features CVR status, provide information support to the cardiologist for diagnosis using the "ARM-Cardiologist" reference system; improve the accuracy of early diagnosis (risk of) cardiovascular diseases and carry a warning on the classification of patients at risk for coronary heart disease from birth based on the results of genetic analysis.
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关键词
cardiology,coronary heart disease,heart electronic model,polymorphism cardiogenic,decision support system,coronary heart disease risk factors,cholestero
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