Genetic Factors Of Renal Survival In Patients With Chronic Kidney Disease
RESEARCH JOURNAL OF PHARMACEUTICAL BIOLOGICAL AND CHEMICAL SCIENCES(2018)
摘要
This paper presents the results of the study of associations of polymorphic loci of chemokines (+1931A/T CCL4 (rs1719153), A/G CXCL11 (rs4512021), -403A/G CCL5 (rs2107538), C/G CCL2 (rs2857657), - 801G/A CXCL12 (rs1801157)) with renal survival in patients with chronic glomerulonephritis. It was established that AA and CXCL11 AG genotypes (rs4512021) (p=0.05) are the marker of high creatinine level in patients with chronic glomerulonephritis.
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关键词
chronic kidney disease,chemokine genes,genetic polymorphism,creatinine level
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