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Effects of Agaricus blazei polypeptide on cell senescence by regulation of Keap1/Nrf2/ARE and TLR4/NF-κBp65 signaling pathways and its mechanism in D-gal-induced NIH/3T3 cells

Qingxia Feng,Xuechun Lu,Guangxin Yuan,Qian Zhang,Liping An

Journal of Functional Foods（2020）

Cited 8|Views15
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Abstract
•Three active components ABp-RRQ, ABp-RQR and ABp-TRAR were obtained.•ABp-RQR was the main active component to alleviate the oxidative inflammatory reactions.•ABp-RQR play an anti-aging role by regulating Nrf2/ARE and TLR4/NF-κBp65 pathways.
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Agaricus blazei,ABp-RQR,Aging,Nrf2/ARE,TLR4/NF-κBp65
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