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Highly diastereoselective aldol reactions of 3-Fluorooxindoles promoted by MgBr2•OEt2/iPr2NEt

Zi-Bin Qiu,Ling-Yan Chen,Jian Ji,Xinfeng Ren,Ya Li

Journal of Fluorine Chemistry（2020）

Cited 5|Views5
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Abstract
•MgBr2OEt2/iPr2NEt-promoted direct Aldol reactions of 3-fluorooxindoles.•A variety of aromatic aldehydes has been successfully reacted.•Mild reaction conditions.
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Key words
Fluorine,Fluoroalkylation,Aldol reaction,Lewis acid,Addition
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