CER-001 ameliorates lipid profile and kidney disease in a mouse model of familial LCAT deficiency

•LCAT plays a major role in catabolism of HDL mimetics used as pharmaceuticals.•CER-001 ameliorates the lipid profile in LCAT deficient mice.•CER-001 reduces albuminuria in a mouse model of renal disease in LCAT deficiency.•CER-001 restores podocyte proteins expression in Lcat−/− mice with renal disease.