CRISPR/Cas9 System for Efficient Genome Editing and Targeting in the Mouse NIH/3T3 Cells.

Maryam Mehravar,Abolfazl Shirazi,Mohammad Mehdi Mehrazar,Mahboobeh Nazari,Mehdi Banan

Avicenna journal of medical biotechnology（2019）

引用 24|浏览5

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摘要

Therefore, CRISPR/Cas9 system can be highly efficient and specific when gRNAs are designed rationally and provides a powerful approach for genetic engineering of cells and model animals.

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关键词

Cell line,Deletion,Gene editing,Mice

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