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Primary vaccination in adult patients after allogeneic hematopoietic stem cell transplantation – A single center retrospective efficacy analysis

Clara Sattler,Petra Hoffmann,Philipp Yorck Herzberg,Daniela Weber,Barbara Holler,Ute Fehn,Annelie Plentz,Philipp Beckhove,Julia Winkler,Matthias Edinger,Wolfgang Herr,Ernst Holler,Daniel Wolff

Vaccine（2021）

Cited 7|Views5
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Abstract
•Current revaccination strategy is efficient in the majority of alloHSCT patients.•Low B cells and low IgGs are risk factors for failure of vaccination response.•Chronic GVHD does not prevent successful revaccination.•Chronic GVHD increases the risk for low response.•Booster vaccines are associated with high risk of failure to respond to vaccination.
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Key words
Allogeneic hematopoietic stem cell transplantation,Vaccination,Immune response,GvHD,B cell reconstitution
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