A patient with bilateral midbrain syndrome due to Plasmodium falciparum infection - a rare presentation

Cerebral malaria is a serious complication of Plasmodium falciparum infection with a high mortality rate, usually present with diffuse cerebral involvement and rarely with focal neurologic deficit. Here we report a case of a young adult without any risk factors for stroke who presented with quadriparesis and was diagnosed to have bilateral midbrain stroke-like syndrome due to Plasmodium falciparum malaria. This is an unusual presentation of Plasmodium falciparum malaria. In tropical countries like India, all patients who present with fever and neurologic deficit should be tested for malaria.