Intravascular malignant lymphomatosis of the B subtype with intraglomerular localisation: a case report
NEPHROLOGIE(1998)
摘要
We report a case of intravascular malignant lymphomatosis observed in a 71 year-old male and characterised by the presence of a proteinuria in relation to the specific intraglomerular localisation. This malignant lymphoma, usually of the B phenotype, is rare and affects predominantly the central nervous system and the skin. Neoplastic cells home selectively to endothelium. Histological renal infiltration is frequent but a glomerular localisation, with proteinuria, is rare. The mechanism whereby lymphocytes home to endothelium cells is unclear but it could be related to the expression of lymphocyte-endothelium adhesion molecules. When is present the nephrotic syndrome is associated with minimal change disease.
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关键词
intravascular lymphomatosis,glomerular disease,B-lymphocyte,angiotropic large cell lymphoma
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