Effect of dexmedetomidine on delirium during sedation in adult patients in intensive care units: A systematic review and meta-analysis

•Dexmedetomidine is associated with a clinically-small reduction of delirium risk.•Dexmedetomidine does not affect short-term mortality in ICU patients.•Dexmedetomidine is associated with shorter mechanical ventilation duration and ICU stay.•Dexmedetomidine is associated with higher incidence of hypotension and bradycardia.