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HIPEC after neoadjuvant chemotherapy and interval debulking is associated with development of platinum-refractory or -resistant disease

Jessica Jou,Zoe Zimmer,Lindsey Charo, Christopher Yau,Cheryl Saenz,Ramez Eskander,Michael McHale,Jula Veerapong,Steven Plaxe,Pratibha Binder

Gynecologic Oncology（2021）

Cited 7|Views22
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Abstract
•HIPEC is associated with the development of platinum-refractory or -resistant ovarian cancer.•Longer surgical duration when utilizing HIPEC leads to higher complication rates.•Improved selection is needed to identify patients with ovarian cancer who will benefit from HIPEC.
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Key words
HIPEC,Heated cisplatin,Interval debulking,Neoadjuvant chemotherapy,Platinum resistant,Platinum refractory
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