Recommendations for clinical research in children presenting to primary care out-of-hours services.

Anouk Weghorst,Gea Holtman, Pien Ingrid Wolters, Heleen Russchen,Freek Fickweiler,Henkjan Verkade,Johan Post,Karin Vermeulen,Boudewijn Kollen,Irma Bonvanie,Marjolein Berger

BJGP open（2020）

Cited 5|Views35

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Abstract

The informed consent procedure and off-protocol use of study medication affect the inclusion rate but had little effect on selection. A parallel cohort study alongside the RCT can help evaluate selection bias, and a pilot study can reveal potential barriers to inclusion.

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Key words

Cardiovascular disease,Clinical (general),Clinical (physical),Comorbidity,Continuity of care,Diabetes,Epidemiology,Research methods

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