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MicroRNA-638 induces apoptosis and autophagy in human liver cancer cells by targeting enhancer of zeste homolog 2 (EZH2)

Environmental Toxicology and Pharmacology(2021)

Cited 20|Views23
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Abstract
•MicroRNA-638 is downregulated in liver cancer tissues and cell lines.•Overexpression of miR-638 inhibits liver cancer cell proliferation.•Overexpression of miR-638 induces apoptosis and autophagy in liver cancer cells.•MicroRNA-638 exerts its effects by targeting enhancer of zeste homolog 2(EZH2).
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Key words
MicroRNA,Liver cancer,Apoptosis,Autophagy,Anti-proliferative,Western blotting
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