Evaluation of the clinical impact of the differences between planned and delivered dose in prostate cancer radiotherapy based on CT‐on‐rails IGRT and patient‐reported outcome scores

Sensitivity of bladder to clinical variations of dose accumulation indicates that an automated solution based on a DIR that considers inter-fractional organ deformation could recommend intervention. This is intended to achieve additional rectum sparing in cases that indicate higher than expected dose accumulation early during patient treatment in order to prevent acute severity of bowel symptoms.