Screening value of neutrophil to lymphocyte ratio in patients with heart failure caused by dilated cardiomyopathy

Objective:To investigate the screening value of peripheral blood neutrophil to lymphocyte ratio (NLR) inpatients with heart failure (HF) due to dilated cardiomyopathy (DCM).Method:A total of 264 patients with DCM-HF were recruited from September 2015 to December 2017, with 236 healthy individuals as the control group.The NLR between DCM-HF patients and healthy controls were analyzed, and its diagnostic value was evaluated using the ROC curve.Besides, we assessed the relationship between NLR levels and New York Heart Association (NYHA) functional classes in patients with DCM-HF.Result:The NLR of DCM-HF patients was 2.92±1.44 and healthy controls was 1.65±0.51.As NYHA functional classes increased, NLR (P<0.001) also increased significantly.The NLR cutoff value predicting DCM-HF was 1.94 with 73.1％ sensitivity and 75.0％ specificity;the area under the curve for DCM-HF was 0.809 (95％CI:0.772-0.846).Conclusion:NLR is associated with the severity of chronic heart failure in DCM-HF.