Altered Reticulum-Mitochondria Interactions Contribute to Mitochondrial Ca2+ Signaling Impairment and Diabetic Cardiomyopathy

Maya Dia,Ludovic Gomez,Helene Thibault,Bruno Pillot,Christelle Leon,Yves Gouriou,Nolwenn Tessier,Emily Tubbs,Nadia Bendridi,Michel Ovize,Jennifer Rieusset,Melanie Paillard

CIRCULATION（2019）

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摘要

Introduction: Type 2 diabetic cardiomyopathy has been linked to Ca2+ signaling alterations, notably a decreased mitochondrial Ca2+ uptake. Uncovering of Ca2+ microdomains between cardiac mitochondr...

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