Poor Recovery From Receptor Tyrosine Kinase Inhibitor Cardiotoxicity is Linked to Toxic Effects on Cardiac Stem Cells

Andrew J. Smith,Prashant Ruchaya,Robert Walmsley, Kathleen E. Wright,Bernardo Nadal-Ginard, Georgina M. Ellison-Hughes

CIRCULATION(2018)

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摘要
Introduction: Receptor tyrosine kinase inhibitors (RTKIs) improve cancer survival but have cardiotoxic side effects, the mechanisms for which warrant further investigation. Endogenous cardiac stem ...
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