In Situ Generation of Core-Shell Protein-Based Microcapsules with Regulated Ion Absorbance Capacity

In this study, we presented a way to generate organic/protein hybrid core-shell micro-compartment structure by in situ generating poly(o-phenylenediamine) (POPD) nanoparticles inside a robust and flexible protein-based shell. Both the size and number of the generated POPD core inside the protein microcapsules could be well varied by using different oxidants including, H2O2, tert-butyl hydroperoxide (TBHP) and glucose oxidase (GO)/ glucose (Glu). Significantly, via operating the membrane permeability by either the cleavage of the conjugated polymer or additional formation of tannic acid/Fe3+ complex outer shell, the adsorption capacity towards Cu2+ of the constructed multiple cores in single shell model could be well modulated. In general, our studies contribute to the establishment of an improved model with its potential applications in catalysis system, biotechnology and biomedicine.