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ZIF-8 Catalysed Efficient Synthesis of Dicyano Alkyl Quinoline Derivatives in Aqueous Medium

Usharani Parimi,Madhavi Nannapaneni

CHEMISTRYSELECT（2020）

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Abstract
A facile ZIF-8 catalyzed method has been developed for the synthesis of dicyano alkylquinoline derivatives from malononitrile, aldehydes and substituted quinaldines in an aqueous medium. This protocol offers simple, and mild reaction conditions for the preparation of alkyl quinolines in higher yields.
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Key words
C-H activation,Heterogeneous catalysis,Quinoline,Water,Zeolite imidazolate frameworks
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