Schistosoma mansoni venom allergen-like protein 6 (SmVAL6) maintains tegumental barrier function

Samirah Perally,Kathrin K. Geyer,Priscila S.G. Farani,Iain W. Chalmers,Narcis Fernandez-Fuentes, Daniel R. Maskell,Benjamin J. Hulme,Josephine Forde-Thomas,Dylan Phillips,Leonardo P. Farias,James J. Collins,Karl F. Hoffmann

International Journal for Parasitology（2021）

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摘要

•Smval6 is expressed in oral/ventral suckers, oesophageal gland and mesenchymal cells of Schistosoma mansoni.•Smval6 knockdown increases surface membrane permeability.•SmVAL6 interacts with Sm14 and DLC proteins.

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关键词

Venom allergen-like,Schistosoma mansoni,Tegument

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