Phylogenetic Analysis Revealed The Dissemination Of Closely Related Epidemic Vibrio Cholerae O1 Isolates In Laos, Thailand, And Vietnam

Masatomo Morita,Kazuhisa Okada,Tetsu Yamashiro,Tsuyoshi Sekizuka,Amonrattana Roobthaisong,Warawan Wongboot,Siriporn Chantaroj,Nguyen Dong Tu,Phonepadith Xangsayarath,Noikaseumsy Sithivong,Khambai Noilath,Arounnapha Vongdouangchanh,Makoto Kuroda,Shigeyuki Hamada,Hidemasa Izumiya, Makoto Ohnssishi

OPEN FORUM INFECTIOUS DISEASES（2020）

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摘要

We performed whole-genome sequencing of Vibrio cholerae O1 isolates from Laos, Thailand, and Vietnam, where cholera outbreaks occurred, to determine their genetic lineages. Core genome phylogenetic analysis revealed that the isolates located in same lineage without regional clusters, which suggests that closely related strains circulated in Southeast Asia.

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phylogeny, Southeast Asia, Vibrio cholerae O1, whole-genome sequencing

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