Prescription of interleukin-1 inhibitors in a French adult cohort of familial Mediterranean fever

Antoine Fayand,Léa Savey,Stéphanie Ducharme-Bénard,Gilles Grateau,Sophie Georgin-Lavialle

European Journal of Internal Medicine（2021）

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摘要

•Colchicine can prevent attacks of familial Mediterranean Fever (FMF) in most cases•Interleukin-1 inhibitors are efficient in FMF patients resistant to colchicine•IL-1 inhibitors were frequently prescribed for AA amyloidosis FMF with kidney failure•IL-1 inhibitors are useful in case of acquired neoplastic or inflammatory comorbidity•IL-1 inhibitor can be withdrawn in FMF patients with AAA after kidney transplantation

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关键词

Familial Mediterranean fever,MEFV,Anti-IL1 biotherapy,Anakinra,Canakinumab

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