A Case Of Non-Bullous Pemphigoid Induced By Igg4 Autoantibodies Targeting Bp230

Bullous pemphigoid (BP) is an autoimmune blistering disorder characterized by tense blisters and urticarial erythema. However, more than 20% of patients with BP do not present typical blister formation, but instead present pruritic erythema, a condition called nonbullous pemphigoid (NBP).1,2 The present report is the first to address IgG subclasses of autoantibodies in NBP. We describe a case of NBP with IgG4 autoantibodies alone targeting BP230 but not BP180.