Essential Tremor – A Cerebellar Driven Disorder?

Mohamed Fasil Ibrahim, Jessica C Beevis,Ruth M Empson

Neuroscience（2021）

引用 17|浏览5

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摘要

•Essential tremor (ET) is the most prevalent tremor and movement disorder.•Essential tremor currently has no definitive cure.•We suggest the Purkinje Neuron-Deep Cerebellar Nuclei circuit as a key driver of ET.•Fixing dysfunctional timing in this circuit may generate effective therapies for ET.

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BCs,CFs,CS,DBS,DCN,EAAT,ET,GRID2,IO,IPSCs,LTD,mGluR1,PD,PFs,PN,PT,SCA1,SS,TMS,vGAT,VIM

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