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Polyvinyl alcohol-based electrospun matrix as a delivery system for nanoemulsion containing chalcone against Leishmania (Leishmania) amazonensis

Daniela Coelho,Beatriz Veleirinho,Letícia Mazzarino,Thaís Alberti,Elizandra Buzanello,Regina Eva Oliveira,Rosendo Augusto Yunes,Milene Moraes,Mário Steindel,Marcelo Maraschin

Colloids and Surfaces B: Biointerfaces（2021）

Cited 13|Views33
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Abstract
•Nanotechnological strategies increase cytotoxic activity of chalcone in vitro.•Nanostructures system to improve leishmanicidal toxicity against L. amazonensis.•Two nanotechnology methods associated for treatment of cutaneous leishmaniasis.•PVA matrix associated with chalcone's nanoemulsion for leishmaniasis treatment.
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Key words
Cutaneous leishmaniasis,Nanoemulsions,Trans-chalcone,Polyvinyl alcohol electrospinning
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