PCLiON: An Ontology for Data Standardization and Sharing of Prostate Cancer Associated Lifestyles

•Lifestyle medicine, which has garnered wide attention in recent years, can be applied to prostate cancer (PCa) prevention and treatment.•Given the heterogeneity of PCa associated lifestyle data, PCLiON was developed as a user-friendly ontology that covers PCa related lifestyles at individual, social, environmental and medical levels.•Integrating 397 lifestyles and lifestyle-related factors associated with PCa, PCLiON is the first of its kind for a specific disease.•Through the bilingual online platforms, complex lifestyle research data can be transformed into standardized, reliable and responsive knowledge, which can promote the shared-decision making on lifestyle intervention and assist patients in lifestyle self-management toward the goal of PCa targeted prevention.