MicroRNA-150 affects endoplasmic reticulum stress via MALAT1-miR-150 axis-mediated NF-κB pathway in LPS-challenged HUVECs and septic mice

•MiR-150 is downregulated in LPS-induced HUVECs.•MiR-150 restrains LPS-induced inflammation, ER stress and apoptosis in HUVECs.•MALAT1 serves as a ceRNA for miR-150.•MiR-150 axis affects LPS-induced ER stress and inflammation via MALAT1-mediated NF-κB pathway.•MiR-150 represses ER stress and inflammation in PAECs isolated from septic mice.