Emerging potential of cannabidiol in reversing proteinopathies

•Proteinopathy is the common hallmarks of many age-related neurodegenerative disorders.•Activation of proteostasis can reverse proteinopathies and halt neurodegenerations.•Cannabidiol can boost proteostasis through diverse signaling pathways of proteostasis.•Cannabidiol reduces oxidative stress and neuroinflammation of brain.•Cannabidiol modulates protein clearance system and also inhibits Ca2+ induced protein misfolding.