Keynote Prescription in Homoeopathy: A Prospective Series of Fifteen Consecutive Cases

Abstract Background Homoeopathy is a system of therapeutics which has a holistic approach towards diseased individual. Prescription in homoeopathy is based on individualisation which can be achieved in various ways. Keynote method is one of such various ways of prescription which needs to be validated by documentation of adequate and valid evidences in its favour. Methods This article presents a series of 15 consecutive cases in which prescriptions were made on the basis of keynote. The outcome was assessed using Outcome Related to Impact on Daily Living (ORIDL) and Measure Yourself Medical Outcome Profile (MYMOP-2) scale. Modified Naranjo criteria were used to find out any possible causal attribution. Result The results reflected improvement in ORIDL scale (+2 and +3). MYMOP-2 for Symptom 1 showed reduction in mean score from 5.60 (standard deviation [SD]: 0.63) to 2.67 (SD: 0.72) after a treatment period of 6 weeks. The reduction was statistically significant (mean difference 2.93 with 95% confidence interval: 2.6–3.2, t-score 19.1382, p < 0.001, paired t-test). The score of Modified Naranjo criteria ranged from 6 to 9. Thus these 15 cases derived the adequate subjective evidences in favour of keynote prescription. Further documentation and studies are warranted.