Pharmacologic considerations in patients with osteoporosis undergoing lumbar interbody fusion: a systematic review

Sauson Soldozy,Danyas Sarathy,Anthony Skaff,Samuel R. Montgomery,Steven Young,Bhargav Desai,Jennifer D. Sokolowski,Avery L. Buchholz,Mark E. Shaffrey,Hasan R. Syed

Clinical Neurology and Neurosurgery（2020）

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摘要

•The use of teriparatide demonstrates improved fusion rates and reduced screw loosening.•Teriparatide combined with denosumab may augment spinal fusion.•Teriparatide more consistently improves fusion when compared to bisphosphonates•Vitamin D may increase fusion rates at early follow-up.

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关键词

Lumbar interbody fusion,Osteoporosis,Bisphosphonates,Teriparatide

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