UV-triggered polymerization of polycatecholamines enables the production of organ-on-chips inside a biosafety cabinet

Applied Materials Today(2020)

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摘要
•UV-triggered polymerization of catecholamine materials forming polydopamine and polynorepinephrine to implement organ-on-a-chip (OOC).•UV-light of a standard biosafety cabinet utilized for the polymerization of PDMS substrates.•Three different types of OOCs created using this technique:(i)Plasma-bonded, polymer-coated chips,(ii)UV-bonded, polymer-coated chips,(iii)projection coated fluid wall chips.•The UV-light and the catecholamine material together offer a simple yet effective technique for implementing OOC.
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关键词
Organ-on-a-chip,microfluidics,surface modification,UV-polymerization,Polydopamine,Polynorepinephrine,polycatecholamine
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