The majority of major amputations after resuscitative endovascular balloon occlusion of the aorta are associated with preadmission trauma

The majority of major amputations in patients undergoing REBOA were secondary to the initial traumatic mechanism. Injury type and severity, as well as initial hemodynamic derangements are associated with mortality after REBOA. Despite concerns about prohibitive limb complications of REBOA, baseline injuries appear to be the primary cause of limb loss, but further prospective analysis is needed.