Fas Ligand (Fasl) Expression Imaging Using A Tc-99m Labeled Anti-Fas Ligand Antibody (Fasl-Ab) In Lpr/Lpr Mice.

Abstract 1082Introduction:Apoptosis can be initiated by Fas:FasL cell surface interaction resulting in programmed cell death. To effectively apply apoptosis therapy it is important to measure FasL up-regulation in vivo. We present data to show Tc-99m-labeled FasL-Ab retained high binding affinity to