Construction of industrial xylose-fermenting Saccharomyces cerevisiae strains through combined approaches

Process Biochemistry(2020)

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摘要
•A combination of point mutation, mating, adaptation, and haploidization was used.•Sugar uptake and ethanol production were enhanced by adaptive evolution.•Evolved strains had strong tolerance to inhibitors in the pretreated straw slurry.
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关键词
Lignocellulosic bioethanol,Xylose fermentation,Redox imbalance,Evolutionary engineering,Saccharomyces cerevisiae
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