Primary fallopian tube carcinoma clinically manifested as vaginal adenocarcinoma in a post-hysterectomy patient: a case report and literature review

Objective: The present authors describe the first case of a primary fallopian tube carcinoma (PFTC) clinically manifested as vaginal adenocarcinoma in a post-hysterectomy patient, and it reminds of the importance to perform bilateral salpingectomy during hysterectomy for a benign condition. Case Report: A 65-year-old woman with a history of hysterectomy presented with vaginal bleeding. Localized vaginal adenocarcinoma was diagnosed after the MRI, PET-CT scan, and biopsy. However, the final diagnosis of primary fallopian tube high grade serous adenocarcinoma was made after optimal laparoscopic cytoreductive surgery. She received chemotherapy with carboplatin and docetaxel given once every three weeks for six cycles. Conclusion: When the imaging results were indistinguishable, post-hysterectomy vaginal bleeding could be the only early symptom of PFTC, and bilateral salpingectomy is important to help prevent re-intervention for malignant or benign fallopian tube pathology. It still requires more research to preoperatively find a better diagnostic method for PFTC.