Su1071 ROLE OF GASTROINTESTINAL ENDOSCOPISTS FOR DETECTION AND TREATMENT OF SUPERFICIAL HYPOPHARYNGEAL CANCER

In Japan, the number of superficial hypopharyngeal cancers, detected by gastrointestinal endoscopists (GE) and cooperatively treated by both GE and head and neck surgeon, is increasing. We aimed to clarify the role of GEs in detection and treatment of superficial hypopharyngeal cancer. A total of 103 consecutive patients with superficial (Tis, T1 and T2) hypopharyngeal cancer who received treatment at department of head and neck (H&N) surgery, Kumamoto University Hospital from October 2013 to October 2018 were enrolled. We investigated the reason for the detection of superficial hypopharyngeal cancer and evaluated the short term outcome of the patients who underwent endoscopic laryngopharyngeal surgery (ELPS). Out of 103 patients, 96(93.2%) were males and 7(6.8%) were females. The average age was 67.9 years of age (range: 43-88 years). Seventy eight and 25 of 103 (75.7% and 24.3%) patients were detected by GEs and Ear Nose Throat (ENT) physicians, respectively. The most frequent reasons for examinations by GEs and ENT physicians were screening/surveillance for esophageal cancer (28 of 78, 35.9%) and pharyngeal discomfort screening (10 of 25, 40.0%), respectively. The T-factors at diagnosis were Tis: 14 cases, T1: 39 cases and T2: 50 cases. The initial treatments were ELPS: 41cases, chemoradiotherapy: 40 cases, radiotherapy: 16 cases, surgery: 4 cases, chemotherapy: 2 cases. Among the patient who underwent ELPS, the median follow-up was 36 months, 3-year-overall survival (OS) was 95.1%. Cause specific survival was 100%. No adverse event was observed. The proportion of superficial hypopharyngeal cancer detection by ENT physicians is much smaller than by GEs. A careful examination of hypopharynx should be conducted by GEs. ELPS performed by GEs and H&N surgeons may improve the QOL and prognosis in patient with superficial hypopharyngeal cancer. GE plays an important role not only for early detection but for treatment of superficial hypopharyngeal cancer.