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坏死松解性肢端红斑一例

Chinese Journal of Dermatology(2019)

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Abstract
患者女,25岁,双足部皮疹伴瘙痒10年.皮肤科情况:双足趾背及邻近足背、右踝伸侧、左跟腱可见边界清楚的暗红色斑块,上覆灰褐色鳞屑.实验室检查:血清丙型肝炎抗体阴性,丙型肝炎病毒核酸定量正常.右侧足背皮损组织病理:表皮角化过度伴角化不全,棘层不规则增生,棘层中上部散在角化不良细胞和坏死角质形成细胞,基底细胞局灶性液化变性;真皮浅中层小血管扩张,周围少量淋巴细胞浸润.诊断:不伴丙型肝炎的坏死松解性肢端红斑.治疗2个月后皮疹完全消退,遗留色素沉着.
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Key words
Hepatitis C,Necrolytic migratory erythema,Necrolytic acral erythema
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