Exploration on the clinical manifestation, diagnosis and treatment of Sparganosis mansoni
Chinese Pediatric Emergency Medicine(2019)
Abstract
目的\r\n探讨儿童曼氏裂头蚴病的临床表现及诊断、治疗方法,提高临床医生对本病的认识。\r\n\r\n\r\n方法\r\n对近期我院诊断及治疗的5例曼氏裂头蚴病患儿临床资料及诊治过程进行整理分析,并结合文献进行复习。\r\n\r\n\r\n结果\r\n5例患儿中男3例、女2例,年龄4~12岁。主要的临床表现为反复发热、肝脾肿大、腹痛腹胀、浆膜腔积液,1例患儿出现皮下结节。实验室检查异常包括嗜酸性粒细胞增多及血沉增快。5例患儿均进行血寄生虫抗体检测诊断,其中1例行包块活检并予组织病理学及基因二代测序确诊。5例患儿均经吡喹酮治疗后恢复。\r\n\r\n\r\n结论\r\n寄生虫类疾病时有散发,临床医生面对反复发热、肝脾肿大、浆膜腔积液、皮下包块及外周血嗜酸性粒细胞明显增高的患儿需考虑到该病。分子诊断技术在诊断方面有其独特优势。吡喹酮是治疗该病的有效药物,但部分病例应用常规剂量吡喹酮治疗可能达不到治愈效果,必要时需重复给药。
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Key words
sparganosis mansoni,clinical manifestation,diagnosis,treatment
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