累及皮肤的套细胞淋巴瘤一例
Chinese Journal of Dermatology（2015）
Abstract
患者女,51岁,确诊套细胞淋巴瘤20个月,四肢红色结节10 d.体检:左颈部及颌下区淋巴结肿大.双侧扁桃体Ⅱ度肿大.左上肢皮损组织病理示真皮及皮下组织见弥漫小淋巴细胞浸润,免疫组化示CD5、bcl-2、CD43、CD20、CyclinD1、λ均阳性,Ki-67阳性率＞70％,CD3、C10、bcl-6、CD23、CD21、κ均阴性.荧光原位杂交检测示t(11∶14)CCND1/IGH融合基因阴性.诊断:累及皮肤的套细胞淋巴瘤.治疗:给予环磷酰胺+多柔比星+长春新碱+泼尼松方案治疗,病情控制,随访中.
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Key words
Lymphoma,mantle-cell,Skin diseases,Rare diseases
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