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基质金属蛋白酶与p53及核因子κB在肿瘤侵袭转移中的研究进展

Jiang-tao YAN,Yun-kui ZHU

Chinese Journal of Asthma（2009）

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Abstract
基质金属蛋白酶在肿瘤侵袭转移中起着非常重要的作用.而基质金属蛋白酶的分泌与p53突变及核因子κB信号传导通路激活相关.因此综述基质金属蛋白酶与p53及核因子κB之间的关系,有利于寻找更多的靶点,以控制肿瘤发生、浸润、转移.
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Key words
Matrix metalloproteinases,p53,Nuelear factor-kappaB,Tumor invasion and metastasis
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