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S100阳性不典型幼年性黄色肉芽肿一例随访观察并文献复习

Chinese Journal of Dermatology(2014)

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Abstract
患者男,3岁,因躯干多发棕黄色丘疹3个月就诊.皮损组织病理学检查,见真皮较多单一核组织细胞、嗜酸性粒细胞及少量淋巴细胞浸润.免疫组化示S100阳性、CD1a部分阳性、CD68阳性.其后原发皮疹颜色渐变暗,部分变平消退,留色素沉着,但仍有新发皮疹.4个月后第2次组织病理学检查显示,除组织细胞、嗜酸性粒细胞外,真皮尚可见少许多核巨细胞.免疫组化示组织细胞S100阴性、CD1a阴性、CD68阳性.诊断:幼年性黄色肉芽肿.
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Key words
Xanthogranuloma,juvenile,S100 proteins,Antigens,CD1
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